Charlotte Jones

Research Assistant

Email:: charlotte.jones2@bcu.ac.uk

Charlotte moved to Birmingham City University (BCU) in January 2022 after working at the University of Birmingham (UoB) as a Research Technician for 11 years. Here she worked on several projects investigating immune responses to Mycobacteria tuberculosis, Salmonella Typhimurium and, briefly, SARS-COV-2 infection. Charlotte has worked with Post Doc researchers as well as training, supervising and mentoring work experience, undergraduate, masters and PhD students. She also has experience creating and complying with standard operating procedures (SOPs), Health and Safety policies and was appointed Deputy Manager of the tuberculosis (TB) Containment Level 3 laboratory at UoB in 2021, where she was responsible for the maintenance of the laboratory, in addition to training students and staff.

Charlotte’s role as a Research Assistant at BCU involves supporting researchers within the Centre of Life and Sport Sciences (C-LaSS) by; performing fund searches/horizon scanning; organising centre meetings and seminars; minute taking; as well as creating and maintaining the C-LaSS Research Hub Moodle page, specifically designed to support early and mid-career C-LaSS researchers. Charlotte is also a member of the Athena Swan Self-Assessment Team (SAT) for the School of Health Sciences, BCU, which achieved Bronze Award in July 2022.

Areas of Expertise

Qualifications

Memberships

Research

Wall, N., Godlee, A., Geh, D., Jones, C… (2021). Latent Cytomegalovirus Infection and Previous Capsular Polysaccharide Vaccination Predict Poor Vaccine Responses in Older Adults, Independent of Chronic Kidney Disease. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America, 73(4), e880–e889.
Domínguez-Medina, C. C., Pérez-Toledo, M., Schager, A. E., Marshall, J. L., Cook, C… (2020). Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface. Nature communications, 11(1), 851.
Perez-Toledo, M., Beristain-Covarrubias, N., Channell, W. M., Hitchcock, J. R., Cook, C. N… (2020). Mice Deficient in T-bet Form Inducible NO Synthase-Positive Granulomas That Fail to Constrain Salmonella. Journal of immunology (Baltimore, Md.: 1950), 205(3), 708–719.
Benedikz, E. K., Bailey, D., Cook, C… (2019). Bacterial flagellin promotes viral entry via an NF-kB and Toll Like Receptor 5 dependent pathway. Scientific reports, 9(1), 7903.
Flores-Langarica, A., Cook, C… (2018). Intestinal CD103+CD11b+ cDC2 Conventional Dendritic Cells Are Required for Primary CD4+ T and B Cell Responses to Soluble Flagellin. Frontiers in immunology, 9, 2409.
Wall, N. A., Dominguez-Medina, C. C., Faustini, S. E., Cook, C. N… (2018). Humoral immunity to memory antigens and pathogens is maintained in patients with chronic kidney disease. PloS one, 13(4), e0195730.
Schager, A. E., Dominguez-Medina, C. C., Necchi, F., Micoli, F., Goh, Y. S., Goodall, M., Flores-Langarica, A., Bobat, S., Cook, C… (2018). IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates. mBio, 9(2), e02379-17.
Newman R, Ahlfors H, Saveliev A, Galloway A, Hodson DJ, Williams R, Besra GS, Cook CN… (2017) Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1. Nat Immunol. 18(6):683-693.
Hitchcock JR, Cook CN… (2015) Inflammation drives thrombosis after Salmonella infection via CLEC-2 on platelets. J Clin Invest. 125(12):4429-46
Flores-Langarica A, Bobat S, Marshall JL, Yam-Puc JC, Cook CN… (2015) Soluble flagellin co-immunization attenuates Th1 priming to Salmonella and clearance by modulating dendritic cell activation and cytokine production.Eur J Immunol. 45(8):2299-311.
Bobat S, Darby M, Mrdjen D, Cook C… (2014) Natural and vaccine-mediated immunity to Salmonella Typhimurium is impaired by the helminth Nippostrongylus brasiliensis.PLoS Negl Trop Dis. 8(12): e3341.
Cunningham AF, Flores-Langarica A, Bobat S, Dominguez Medina CC, Cook CN… (2014) B1b cells recognize protective antigens after natural infection and vaccination. Front Immunol. 5:535.
Ross EA, Flores-Langarica A, Bobat S, Coughlan RE, Marshall JL, Hitchcock JR, Cook CN… (2014) Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function. Eur J Immunol. 44(8):2318-30.
Flores-Langarica A, Marshall JL, Hitchcock J, Cook C… (2012) Systemic flagellin immunization stimulates mucosal CD103+ dendritic cells and drives Foxp3+ regulatory T CELL and IgA responses in the mesenteric lymph node. J Immunol. 189(12):5745-54.